Extended Data Fig. 1: RNAemia and antibody responses after vaccination. | Nature Microbiology

Extended Data Fig. 1: RNAemia and antibody responses after vaccination.

From: Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans

Extended Data Fig. 1

a, Kinetics of RNAemia (genome copies/ml) after JE/YF17D vaccination. Individual vaccinees are connected by blue-dashed line. b, Kinetics of RNAemia (genome copies/ml) after YF17D vaccination. Individual vaccinees are connected by red-dashed line. c, Neutralizing antibody titers (PRNT50) against JE SA 14-14-2 and YF17D 28 days after JE/YF17D (n = 17) or YF17D (n = 16) vaccination, respectively. d, Anti-JE E antibody levels (P/N ratio) and anti-YF E antibody levels (P/N ratio) 28 days after JE/YF17D (n = 17) or YF17D (n = 16) vaccination, respectively. P/N ratio was calculated by dividing the absorbance value of the vaccine sera by that of the day 0 (naïve) sera. Dots represent individual vaccinees. Black horizontal bar represents mean. P values were calculated with two-tailed unpaired Student’s t-test or two-tailed unpaired Mann-Whitney U test. ns, not significant.

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