Fig. 1: Population structure and temporal dynamics of VREfm at UPMC over 6 years.
From: Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium
a, Cluster network diagram of 710 sequenced VREfm genomes constructed using Gephi v0.10. Isolates are grouped and coloured by multilocus ST. Isolates that fall within putative transmission clusters (≤10 SNPs) are connected with grey lines. b, Prevalence of cluster isolates within different STs. Asterisks mark STs that show a higher or lower percentage of clustered isolates compared with the total collection (one-sided, single-proportion hypothesis test). P values were adjusted for multiple comparisons (*P < 0.004): ST1478, P = 0.0002; ST17, P = 0.0008. c, Biannual distribution of STs over the study period. Q1–Q2 = January–June; Q3–Q4 = July–December. The number of samples within each sample period is also noted. Emergent lineages are noted with a black star.
