Extended Data Fig. 7: Fold change in A(H3N2) HAI titers with the difference in years between virus isolation and infection or vaccinated virus using longitudinal data.
From: Breadth of influenza A antibody cross-reactivity varies by virus isolation interval and subtype
Dots and error bars indicate the mean fold change and standard deviation at each difference in isolation time. Coloured lines and shades indicate the mean and 95% CI of fold change estimated from GAM. (a) Fold change in HAI titers with the difference in years between virus isolation and years with PCR confirmation of A(H3N2) infections. Fold changes were calculated for PCR individuals using antisera collected in and a year prior to the PCR positives (data from Fonville et al.5). (b) Fold change in HAI titers with the difference in years between virus isolation and vaccinations. Data from Ertesvåg et al.25 were used. (c) Fold change in HAI titers with the difference in years between virus isolation and vaccinations, stratified by vaccine history. Data from Hinojosa et al.24 were used.
