Extended Data Fig. 8: Chemical disruption of aggresomes and antibiotic survival.
From: Aggresomes protect mRNA under stress in Escherichia coli
a. Representative fluorescence images showing aggresomes (distinct mRNA foci) in cells treated with: Ctrl (untreated), Hex (1,6-hexanediol), or Dox (doxorubicin). b. Quantification of cells containing aggresomes across treatments. Data from a (n = 100 cells per condition; 3 replicates). c-d. Cell survival rates (log scale) after 4-hour antibiotic exposure: c. Ampicillin; d. Kanamycin (n = 3 independent biological replicates, mean ± SE). Scale bar: 1 μm (a). Two-sided unpaired Student’s t-test used in comparison; error bars = SE.
