Extended Data Fig. 2: Detection of RdRp gene of Tomato mosaic virus (ToMV) and indicated genes of EBV from oral swabs of SjD and HC subjects.
From: Vientovirus capsid protein mimics autoantigens and contributes to autoimmunity in Sjögren’s disease
(a) Representative PCR bands of indicated genes from oral swabs. (b) Quantifications of relative band intensities normalized to ACTB and the semi-quantitative levels were shown in the heatmap. (c) Two-sided Spearman’s correlation between relative band intensity of ToMV and anti-SSA/Ro52 level was shown. (d) Two-sided Spearman’s correlation between the relative band intensity of ToMV and unstimulated salivary flow rate (uSFR) was shown. (e) Two-sided Spearman’s correlation between relative band intensity of EBV genes and indicated clinical parameter were shown in the heatmap. uSFR, unstimulated salivary flow rate; sSFR, stimulated salivary flow rate; ESSPRI, EULAR Sjögren’s Syndrome Patient Reported Index; ESSDAI, EULAR Sjögren’s Syndrome Disease Activity Index. *, P < 0.05, **, P < 0.01, ***, P < 0.001.
