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Biosensing

Seeing quick beats with atomically thick sheets

Nature Photonics volume 19, pages 445–446 (2025)Cite this article

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Local measurements of biological voltage production are key drivers of understanding in neurobiology and neurological and cardiac pathophysiology. Researchers have now shown that exciton–trion conversion in a two-dimensional semiconductor, MoS2, can be used to optically image cardiomyocyte action-potentials in real-time.

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Fig. 1: Label-free voltage imaging using luminescent MoS2 monolayers.

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Authors and Affiliations

  1. The University of Melbourne School of Physics, Parkville, Victoria, Australia

    Daniel J. McCloskey

  2. ARC Centre of Excellence in Quantum Biotechnology, The University of Melbourne School of Physics, Parkville, Victoria, Australia

    Daniel J. McCloskey

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  1. Daniel J. McCloskey
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Correspondence to Daniel J. McCloskey.

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Competing interests

D.J.M. is an inventor on a pending patent for diamond-based optical voltage imaging technology (patent application numbers AU2022271350, US2024241166, EP4334708), and is a founder and shareholder of Chromos Laboratories Pty Ltd, a company that is commercializing diamond-based optical voltage imaging platforms.

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McCloskey, D.J. Seeing quick beats with atomically thick sheets. Nat. Photon. 19, 445–446 (2025). https://doi.org/10.1038/s41566-025-01661-w

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