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LIVER

Novel insights into liver homeostasis and regeneration

Nature Reviews Gastroenterology & Hepatology volume 18, pages 369–370 (2021)Cite this article

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Studies of liver regeneration after injury have provided knowledge of the role of external signals and internal metabolic and regenerative pathways. However, less is understood about homeostatic maintenance of normal liver size in the absence of external injury. Three important new studies explore liver regeneration and homeostasis using novel lineage tagging of hepatic cells and single-cell RNA transcriptomics.

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  1. Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

    George K. Michalopoulos

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  1. George K. Michalopoulos
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Correspondence to George K. Michalopoulos.

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The author declares no competing interests.

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Michalopoulos, G.K. Novel insights into liver homeostasis and regeneration. Nat Rev Gastroenterol Hepatol 18, 369–370 (2021). https://doi.org/10.1038/s41575-021-00454-0

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