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Scaling the immune incline in PDAC

Nature Reviews Gastroenterology & Hepatology volume 18, pages 453–454 (2021)Cite this article

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Pancreatic ductal adenocarcinoma (PDAC) reflects the current challenge for immuno-oncology: to develop new drugs for cancers that are resistant to current immunotherapies. Here, we argue for a need to use patients to uncover new strategies that activate anti-tumour immunity.

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Fig. 1: The cancer immune incline.

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Acknowledgements

This work was supported by a Damon Runyon Clinical Investigator Award to V.P.B and an NIH U01 CA224175 to V.P.B.

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Authors and Affiliations

  1. Immuno-Oncology Service, Human Oncology and Pathogenesis Program; Hepatopancreatobiliary Service, Department of Surgery; Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Luis A. Rojas & Vinod P. Balachandran

  2. David M. Rubenstein Center for Pancreatic Cancer Research; Parker Institute for Cancer Immunotherapy; Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Vinod P. Balachandran

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  1. Luis A. Rojas
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  2. Vinod P. Balachandran
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Correspondence to Vinod P. Balachandran.

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Rojas, L.A., Balachandran, V.P. Scaling the immune incline in PDAC. Nat Rev Gastroenterol Hepatol 18, 453–454 (2021). https://doi.org/10.1038/s41575-021-00475-9

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