Metal–organic frameworks hold immense application potential, but their stability and environmental safety remain barriers to industrial translation. Embracing the ‘safe and sustainable by design’ framework would, however, set a transformative pathway to the development of robust, recyclable metal–organic frameworks, ensuring functionality, minimal ecological impact and alignment with circular economy and chemical sustainability goals.
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Acknowledgements
S.C. acknowledges the UKRI – NERC Independent Research Fellowship (Grant number UKRI187) for supporting this work. D.M. acknowledges NanoDTC Cambridge – EPSRC EP/S022953/1. I.L. and S.K.M. acknowledge the Royal Society International Exchanges grant (IES\R2\232158).
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Chakraborty, S., Menon, D., Mikulska, I. et al. Make metal–organic frameworks safe and sustainable by design for industrial translation. Nat Rev Mater 10, 167–169 (2025). https://doi.org/10.1038/s41578-025-00774-6
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DOI: https://doi.org/10.1038/s41578-025-00774-6
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