This month’s Under the Lens discusses progress towards bridging the resolution gap in correlative super-resolution light and electron microscopy, and highlights its application for visualizing bacterial infections.
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References
Hampton, C. M. et al. Correlated fluorescence microscopy and cryo-electron tomography of virus-infected or transfected mammalian cells. Nat. Protoc. 12, 150–167 (2017).
van Elsland, D. M. et al. Ultrastructural imaging of Salmonella–host interactions using super-resolution correlative light-electron microscopy of bioorthogonal pathogens. ChemBioChem 19, 1766–1770 (2018).
Wang, L. et al. Solid immersion microscopy images cells under cryogenic conditions with 12 nm resolution. Commun. Biol. 2, 74 (2019).
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Dobbie, I.M. Bridging the resolution gap: correlative super-resolution imaging. Nat Rev Microbiol 17, 337 (2019). https://doi.org/10.1038/s41579-019-0203-8
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DOI: https://doi.org/10.1038/s41579-019-0203-8