This month’s Genome Watch highlights the systematic discovery of defence systems, paving the way to decode novel genetic functions and further our understanding of microbial warfare.
Enjoying our latest content?
Log in or create an account to continue
- Access the most recent journalism from Nature's award-winning team
- Explore the latest features & opinion covering groundbreaking research
or
References
Doron, S. et al. Systematic discovery of antiphage defense systems in the microbial pangenome. Science 359, eaar4120 (2018).
Payne, L. J. et al. Identification and classification of antiviral defence systems in bacteria and archaea with PADLOC reveals new system types. Nucleic Acids Res. 49, 10868–10878 (2021).
Tesson, F. et al. Systematic and quantitative view of the antiviral arsenal of prokaryotes. Preprint at bioRxiv https://doi.org/10.1101/2021.09.02.458658 (2021).
Abby, S. S. et al. MacSyFinder: a program to mine genomes for molecular systems with an application to CRISPR-Cas systems. PLoS ONE 9, e110726 (2014).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Cazares, A., Figueroa, W. & Cazares, D. Diversity of microbial defence systems. Nat Rev Microbiol 20, 191 (2022). https://doi.org/10.1038/s41579-022-00702-3
Published:
Version of record:
Issue date:
DOI: https://doi.org/10.1038/s41579-022-00702-3
This article is cited by
-
Evolutionary diversification and succession of soil huge phages in glacier foreland
Microbiome (2025)
-
Engineering the gut microbiome
Nature Reviews Bioengineering (2023)
