Fig. 1: Visible phenotypes of mutations in long non-coding RNA genes in mice163.
From: Long non-coding RNAs: definitions, functions, challenges and recommendations
The following long non-coding RNAs (lncRNAs) are listed in the figure underneath their associated phenotypes: Airn, antisense of IGF2R non-protein-coding RNA147,435; Charme, chromatin architect of muscle expression436; Chaserr, CHD2 adjacent, suppressive regulatory RNA437; Fendrr, FOXF1 adjacent non-coding developmental regulatory RNA165,438; Firre, functional intergenic repeating RNA element316; Gaplinc, gastric adenocarcinoma predictive long intergenic non-coding RNA200; H19, clone pH19 (ref. 439); Handsdown, downstream of the protein-coding gene Hand2 (ref. 440) Kcnq1ot1, Kcnq1 overlapping antisense transcript 1 (ref. 441); linc-Brn1b, long intergenic non-coding RNA (lincRNA) downstream of the Brn1 protein-coding gene165; linc-Epav, endogenous retrovirus-derived lncRNA positively regulates antiviral responses442; lincRNA-Cox2, lincRNA downstream of the inflammation response gene Cox2 (ref. 443); lincRNA-Eps, lincRNA involved in erythroid prosurvival201; lnc-Lsm3b, interferon-inducible non-coding splice variant of the U6 small nuclear RNA-associated Sm-like protein lsm3 gene444; Maenli, master activator of engrailed1 in the limb165; Mdgt, midget165; Meg3, maternally expressed gene 3 (also known as Gtl2)445,446; Norad, non-coding RNA activated by DNA damage447; Peril, perinatal lethal long non-coding RNA165; Pnky, pinky (also known as lnc-Pou3f2)448; Tug1, taurine upregulated gene 1 (refs. 165,166,449) Upperhand, lncRNA upstream of the Hand2 cardiomyocyte transcription factor locus318; Xist, X-inactive-specific transcript450. Figure courtesy of Daniel Andergassen and John Rinn.
