Table 2 Main components of a haematopoietic stem cell transplantation service
Unit | Setting | Contribution to HSCT service |
---|---|---|
Neurology | Outpatient | Screening for HSCT eligibility Pre-HSCT assessment of neurological status Post-HSCT monitoring (focused on effectiveness outcomes) |
Haematology | Outpatient and inpatient | Screening for HSCT eligibility (exclusion of contraindications) Mobilization and collection of HSCs Conditioning, HSC reinfusion and recovery Post-HSCT monitoring (focused on safety outcomes, including late effects) |
Neuroradiology | Outpatient | Screening for eligibility Post-HSCT monitoring (focused on MRI outcomes) |
Physiotherapy | Outpatient and inpatient | ‘Pre-habilitation’ Post-HSCT rehabilitation |
Laboratory | Outpatient and inpatient | Screening investigations in blood, CSF, bone marrow and other biological samples Safety monitoring with blood biochemistries and diagnosis and monitoring of infections Investigation of immune recovery |
Reproductive medicine | Outpatient | Fertility counselling before and after HSCT Fertility preservation Assisted reproductive technology |
Health psychology and neuropsychology | Outpatient | Psychological assessment before HSCT Psychological counselling before and after HSCT Neuropsychological testing before and after HSCT Psychiatric evaluation if screening raises concerns |