Extended Data Fig. 9: The entangled tetrameric VP35 wraps around L protein.

(a) EBOV L is shown in grey surface representation, and VP35 protomers are shown in cartoon representation with different colors. (b) Structural conformations of different VP35 protomers. (c) The major atomic interactions between VP35 protomers. The key interacting residues are shown in stick representation. Hydrogen bonds are presented in yellow dash lines, while the hydrogen bonds between the anti-parallel β strands are not shown (left side).