Extended Data Fig. 12: Structural comparison of EBOV L-VP35-suramin complex with SARS-CoV-2 RdRp-suramin and Murine Noroviruses (MNV) RdRp-suramin complex. | Nature

Extended Data Fig. 12: Structural comparison of EBOV L-VP35-suramin complex with SARS-CoV-2 RdRp-suramin and Murine Noroviruses (MNV) RdRp-suramin complex.

From: Structure of the Ebola virus polymerase complex

Extended Data Fig. 12

(a-b) Superimposition of the EBOV L-VP35-suramin with SARS-CoV-2 RdRp-suramin complex (PDB 7D4F) and MNV RdRp-suramin complex (PDB 3UR0) was performed based on the RdRp domain. A close-up view of suramin within the catalytic chamber in the SARS-CoV-2 RdRp-suramin complex (c), EBOV L-VP35-suramin complex (d) and MNV RdRp-suramin complex (e).

Back to article page