Extended Data Fig. 2: Structural comparison of EBOV L-VP35 and HPIV5 L-P complex.

Overall structure of EBOV L-VP35 (a) and HPIV5 L-P complex (PDB 6v85) (b). Overlay of the NTD (c), RdRp (d), PRNTase (e) domains and tetrameric P/VP35 protein (f) between EBOV L-VP35 and HPIV5 L-P complex shows a similar architecture, but with local differences.