Extended Data Fig. 7: Conservation analysis.
From: Plasmid targeting and destruction by the DdmDE bacterial defence system

Conservation analysis of DdmE (a) and DdmD (b). For DdmD, the RecA helicase channel, nuclease active site and dimer interface are highly conserved. c, Conservation of DdmD – DdmE handover complex interface. DdmD(R620) is conserved and is buried within a similarly conserved pocked of DdmE. d, Electrostatics of DdmDE handover complex.