Extended Data Fig. 2: SDET-mediated 1,2-addition of 1a to 6a and design of the first photo-Lewis-acid catalysed lactonisation of alkenoic acids.
From: Unimolecular net heterolysis of symmetric and homopolar σ-bonds
a, 5-phenylpent-3-enoic acid (6a, 1.0 equiv) was exposed to 1a (1.0 equiv) and the corresponding acid additive (0 or 0.5 equiv) in HFIP or iPrOH (c1a = 0.5 M) for 24 h at 19 °C and the indicated irradiation wavelength. b, Alk-3-enoic acids 6a-f (0.5 mmol) were irradiated (405 nm) in the presence of 1a (5 mol%) in HFIP (c6a-f = 0.5 M) for 24 h to 48 h at 35 °C. Yields in parentheses correspond to isolated compounds.
