Extended Data Fig. 9: Sc-RNAseq-based interactome of B cells and plasma cells, and BCR sequence consensus. | Nature

Extended Data Fig. 9: Sc-RNAseq-based interactome of B cells and plasma cells, and BCR sequence consensus.

From: A human autoimmune organoid model reveals IL-7 function in coeliac disease

Extended Data Fig. 9

a, B cell- and plasma B cell-specific immune interactomes derived from scRNA-seq CellPhoneDB analysis showing 117 unique B and plasma-cell driven interactions in gliadin-treated organoids and absence of unique interactions in CLIP, integrated data from n = 4 CeD patients. b, BCR sequence consensus analysis from scRNA-seq of matched CDR3 sequences from active CeD organoids and published anti-TG2 CDR3 sequences categorized by length; n = 3 CeD patients.

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