Extended Data Fig. 12: Additional quantifications of the correlation between functional connectivity and the stability of the decay and ramp.
From: Causal evidence of a line attractor encoding an affective state
a. Illustration of different quantification approaches to the change in activity of non-targeted x1 neurons from Fig. 5e as either the average z-score activity following different stimulus pulses, or the area under the curve (auc). Red vertical lines, photostimulation pulses. b. Left: Correlation between the rate of ramping of the integration dimension obtained from observation of aggression and average z-score of non-targeted x1 neurons measured using the average z-score post third stimulus (r2: 0.01, n.s, n = 8 mice). Right: Correlation between rSLDS time constant obtained from observation of aggression and average z-score across non-targeted x2 neurons measured using the average z-score post third stimulus (r2: 0.87, ***p < 0.001, n = 8 mice). c. Same as b) but calculated from non-targeted x1 neurons measuring the auc of activity post first stimulus. d. Same as c), calculated from non-targeted x1 neurons measuring the average z-score activity. e. Same as c) but calculated from non-targeted x2 neurons measuring the AUC of activity post third stimulus. f. Same as e) but calculated using the average z-score activity. g. Same as e) but calculated post first stimulus. h. Same as g) but calculated using the average z-score activity.
