Fig. 1: A multi-omic survey of the developing human neocortex.
From: Molecular and cellular dynamics of the developing human neocortex
a, Description of the samples used in this study. The diagram was created using BioRender. b, UMAP plots of the snMultiome data, showing the distribution of 33 cell types. c, UMAP plots showing the distribution of age groups (left) and regions (right). d, The proportion of individual cell types across developmental stages and cortical regions. Bars are colour coded by cell types, the legend for which is shown in b. e, The expression of signature TFs in individual cell types (left). Middle, aggregated chromatin accessibility profiles at the promoter of signature TFs across cell types. The blue arrows represent each TF’s transcriptional start site and direction. Right, normalized chromVAR motif activity of signature TFs across cell types.
