Extended Data Fig. 17: Mapping Tri-IPC progenies to reference data.
From: Molecular and cellular dynamics of the developing human neocortex
a, UMAP plot of a reference human ganglionic eminence dataset33. Cells are colour coded by types. b, UMAP plots of human ganglionic eminence cells showing the expression levels of typical marker genes of individual cell types. c, UMAP plots of Tri-IPC-derived INs projected to the human ganglionic eminence dataset. Cells are colour coded by types and the legend can be found in panel d. d, Identities of Tri-IPC-derived INs mapped by Seurat label transfer. e, UMAP plot of mouse astrocytes from a reference developing mouse cortex dataset36. Cells are colour coded by lineages and the legend can be found in panel h. f, UMAP plots of the reference mouse astrocytes showing the expression levels of typical marker genes of individual astrocyte lineages. g, UMAP plots of Tri-IPC-derived astrocytes projected to the reference mouse astrocytes. Cells are colour coded by lineages and the legend can be found in panel h. h, Identities of Tri-IPC-derived astrocytes mapped by Seurat label transfer. i, UMAP plot of human astrocytes at the infancy stage. Cells are colour coded by lineages and the legend can be found in panel l. j, UMAP plots of human astrocytes showing the expression levels of typical marker genes of individual astrocyte lineages. k, UMAP plots of Tri-IPC-derived astrocytes projected to the reference human astrocytes. Cells are colour coded by lineages and the legend can be found in panel l. l, Identities of Tri-IPC-derived astrocytes predicted by SingleCellNet (top) or mapped by Seurat label transfer (bottom). m, Proportion of each SingleCellNet-predicted cell type across GBM samples.
