Extended Data Fig. 2: Cryo-EM analyses of the GGCX–BGP complex.
From: Structure and mechanism of vitamin-K-dependent γ-glutamyl carboxylase
a, Summary of cryo-EM data processing procedures of the GGCX–BGP complex. b, Fourier shell correlation (FSC) curves between two half maps of the GGCX–BGP complex. c, Local resolution of cryo-EM map of the GGCX–BGP complex. Maps are colored according to local resolution, estimated using cryoSPARC. d, Cryo-EM map of the GGCX–BGP (unsharpened) at different contour levels. The strong cholesterol (yellow) is visible at a high contour level, while the unassigned lipid/detergent densities (cyan) are invisible. e, Cryo-EM maps of the major structural elements of GGCX and BGP, as well as the cholesterol and Phosphatidylcholine (PC) in GGCX–BGP complex.
