Extended Data Fig. 5: Models of the propeptides from other VDPs binding to GGCX.
From: Structure and mechanism of vitamin-K-dependent γ-glutamyl carboxylase
a, Propeptide of Prothrombin (residue 26-38) modeled to GGCX. The potential interactions are indicated by dashed lines. The residues of Prothrombin are denoted by underlining. b, Propeptide of F9 (residue 29-41) modeled to GGCX. The potential interactions are indicated by dashed lines. The residues of F9 are denoted by underlining. c, Propeptide of Protein C (residue 25-37) modeled to GGCX. The potential interactions are indicated by dashed lines. The residues of Protein C are denoted by underlining. d, Propeptide of MGP (residue 32-44) modeled to GGCX. The potential interactions are indicated by dashed lines. The residues of MGP are denoted by underlining.
