Extended Data Fig. 6: Structure comparisons of the AlphaFold2-predicted structure of inactive NRG1ANOD-LRR with experimental structures.
From: Balanced plant helper NLR activation by a modified host protein complex
a, The AlphaFold2-predicted structure of inactive NRG1ANOD-LRR resembles that of the corresponding segment of the inactive ZAR1NOD-LRR. The cryo-EM structure of inactive ZAR1-RKS1 (PDB code: 6J5W) and Alphafold2-predicted structure of inactive NRG1ANOD-LRR were aligned with PyMOL. b, The AlphaFold2-predicted structure of inactive NRG1ANOD-LRR and NRG1AWHD-LRR of EDS1-SAG101-NRG1AWHD-LRR were aligned with PyMOL. Structures were shown in cartoon representations. Colour codes are shown as indicated.
