Extended Data Fig. 4: Structural comparison of ADPr-ATP-bound EDS1-SAG101 with EDS1-SAG101-NRG1AWHD-LRR and EDS1-SAG101-NRG1C.
From: Balanced plant helper NLR activation by a modified host protein complex
a, The cryo-EM structures of ADPr-ATP-bound EDS1-SAG101 (PDB code: 7XJP) and EDS1-SAG101 from EDS1-SAG101-NRG1AWHD-LRR were aligned with PyMOL. Colour codes are shown as indicated. b, ADPr-ATP of the cryo-EM structure of EDS1-SAG101-NRG1AWHD-LRR complex. c, ADPr-ATP of the crystal structure of EDS1-SAG101-NRG1C. ADPr-ATP is shown in stick. The cryo-EM density (b) and the electron density (c) surrounding the small molecule are shown in grey mesh. The map was contoured at 1.2 sigma in PyMOL.
