Extended Data Fig. 9: The evolutionary history of APCDD1 and PIEZO2 and their expression patterns.
From: Integrated analysis of the complete sequence of a macaque genome
(a) The syntenic relationship of APCDD1 and PIEZO2 in primates is shown with minimiro, with gene annotations and DupMasker attached to each genome segment. PIEZO2 is located inside an inversion in the primate evolution, while APCDD1 is located near the inversion. (b, c) The bar plot shows the proportion of cell types for expressed cells on APCDD1 (b) and PIEZO2 (c). The proportion differences in expressed cell type are observed in APCDD1 and PIEZO2 between humans and macaques. Ex Neuron, excitatory neuron; Oligo, oligodendrocyte; In Neuron, inhibitory neuron; Astro, astrocyte; OPC, oligodendrocyte precursor cell; Micro: microglia.
