Extended Data Fig. 9: Sequence alignment of MPC and SemiSWEET homologues.
From: Structure of mitochondrial pyruvate carrier and its inhibition mechanism
Sequence alignments of MPC from human, Bovine, Mouse, Chicken, African clawed frog (frog), Black rockcod (Rockcod), Caenorhabditis elegans (C. ele), Lacerta muralis (L. mur), Saccharomyces cerevisiae (Yeast) and SemiSWEET from Vibrio sp (V. sp.), Rickettsia bellii (R. bel.), Leptospira biflexa serovar Patoc (L. bsp.), Fusobacterium (Fus.), Flavobacterium johnsoniae (F. joh.), Escherichia coli (E. coli), Chlorobium phaeobacteroides (C. pha.), Parvimonas micra (P. mic.), Limosilactobacillus reuteri (L. reu). The highly conserved residues between MPC2 and SemiSWEET are indicated by blue circles. Each group of MPC1, MPC2, and SemiSWEET is separated by lines.
