Extended Data Fig. 5: Single-particle cryo-EM data processing pipeline for the FabE complex.
From: A coronavirus assembly inhibitor that targets the viral membrane protein
Schematic representation of the single-particle cryo-EM data processing pipeline for the FabE complex. Major steps include particle picking, 2D classification, initial model generation, 3D classification, refinement, and map sharpening. The final reconstruction yielded a 3.3 Å resolution map. Additional details are described in the single-particle image processing section of the materials and methods. CTF: contrast transfer function.
