Extended Data Fig. 8: Atomic model of SARS-CoV-2 M in complex with Fab-B and CIM-834.
From: A coronavirus assembly inhibitor that targets the viral membrane protein
a, Atomic model of the dimeric complex with residues coloured according to calculated B-factor. b, Zoomed-in view of the inhibitor binding site with the C1 symmetry (left) or C2 symmetry (right)-imposed EM density shown as a blue mesh. c, Map versus model FSC curves for the final refined model, generated in Phenix66. d, Two orthogonal views of the sharpened EM density for CIM-834 shown at a sigma level of 4.8 and 6.5. e, Two orthogonal views of the unsharpened EM density for CIM-834 shown at a sigma level of 4.6 and 5.8.
