Extended Data Table 1 In vitro antiviral activity of CIM-834 against different coronaviruses

From: A coronavirus assembly inhibitor that targets the viral membrane protein

  1. Antiviral activity (EC50) and cytotoxicity (CC50) of CIM-834 against various alpha and beta coronaviruses and against SARS-CoV-2 viruses carrying nirmatrelvir resistance mutations in the Mpro/3CLpro30. ∗Human hepatocellular carcinoma cell line; †Rhesus monkey kidney epithelial cell line; ‡Crandell-Rees feline kidney cell line; §human colorectal carcinoma cell line; ||African green monkey kidney cell line; human airway epithelial cell line; #: maximum 53 ± 7% inhibition at 3 µM.
Back to article page