Abstract
The James Webb Space Telescope (JWST) has revealed unexpectedly rapid galaxy assembly in the early Universe, in tension with galaxy-formation models1,2,3. At the low abundances of heavy elements (metals) and dust typical in early galaxies, the formation of molecular hydrogen and its connection to star formation remain poorly understood. Some models predict that stars form in predominantly atomic gas at low metallicity4,5, in contrast to molecular gas at higher metallicities6. Despite repeated searches7, cold molecular gas has not yet been observed in any galaxy below 7% solar metallicity8. Here we report the detection of rotational emission from molecular hydrogen near the only O-type star in the 3% solar metallicity galaxy Leo P (refs. 9,10) with JWST’s Mid-Infrared Instrument/Medium Resolution Spectroscopy (MIRI-MRS) observing mode. These observations place a lower limit on Leo P’s molecular gas content, and modelling of the photodissociation region illuminated by the O star suggests a compact (≤2.6 pc radius), approximately 104 M⊙ cloud. We also report a stringent upper limit on carbon monoxide (CO) emission from a deep search with the Atacama Large Millimeter/submillimeter Array (ALMA). Our results highlight the power of MIRI-MRS to characterize even small ultraviolet-illuminated molecular clouds in the low-metallicity regime, in which the traditional observational tracer CO is uninformative. This discovery pushes the limiting metallicity at which molecular gas is present in detectable quantities more than a factor of two lower, providing crucial empirical guidance for models of the interstellar medium in early galaxies.
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Data availability
JWST MIRI-MRS data from programme GO-3449 will be available to download from the Mikulski Archive for Space Telescopes (https://mast.stsci.edu) as of 23 May 2025. Data for ALMA Project 2013.1.00397.S are available to download from the ALMA archive (https://almascience.nrao.edu/alma-data). Results from the PDR modelling are available from the authors on request. All other data in this paper have been previously published.
Code availability
The JWST Science Calibration Pipeline is available at https://github.com/spacetelescope/jwst. The CASA software used to process the ALMA data is available at https://casa.nrao.edu. Code to measure and analyse the H2 emission line intensities, uncertainties and upper limits is available at https://github.com/ogtelford/LeoPH2MRS. The PDR modelling software is available at https://github.com/scog1234/SGPDR.
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Acknowledgements
Based on observations with the NASA/ESA James Webb Space Telescope obtained from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. Support for this work was provided by NASA through grant JWST-GO-3449 from the Space Telescope Science Institute under NASA contract NAS5-26555. O.G.T. acknowledges support from a Carnegie-Princeton Fellowship through Princeton University and the Carnegie Observatories. This research was supported in part by grant NSF PHY-2309135 to the Kavli Institute for Theoretical Physics (KITP). S.C.O.G. acknowledges financing from the European Research Council through the ERC Synergy Grant ‘ECOGAL’ (project ID 855130) and from the German Excellence Strategy through the Heidelberg Cluster of Excellence ‘STRUCTURES’ (EXC 2181 - 390900948). A.D.B. acknowledges support from the NSF under award AST-2108140. This paper makes use of Atacama Large Millimeter/submillimeter Array (ALMA) data. ALMA is a partnership of ESO (representing its member states), NSF (USA) and NINS (Japan), together with NRC (Canada), MOST and ASIAA (Taiwan) and KASI (Republic of Korea), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, AUI/NRAO and NAOJ. The National Radio Astronomy Observatory is a facility of the National Science Foundation operated under cooperative agreement by Associated Universities, Inc. This research used NASA Astrophysics Data System Bibliographic Services, adstex and the arXiv preprint server. The following software was used in this analysis: Astropy66,67,68, iPython69, Matplotlib70, NumPy71,72, SAOImageDS9 (ref. 73), SciPy74, CASA60 and SpectralCube75.
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O.G.T., K.M.S. and K.B.W.M. developed the JWST proposal. O.G.T. (PI of JWST-GO-3449) analysed the H2 emission lines in the MIRI-MRS observations of Leo P, made Figs. 1 and 2 and wrote the manuscript. K.M.S. led the design of the JWST observations and reduced the MIRI-MRS data. S.C.O.G. modelled the PDR to constrain the emitting H2 temperature and made Extended Data Fig. 1. E.J.T. reduced the ALMA data and calculated the upper limit on LCO in Leo P. A.D.B., R.J.R.V. and all authors contributed to interpretation of the results and to the manuscript.
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Extended data figures and tables
Extended Data Fig. 1 PDR modelling suggests a low temperature for the detected H2.
H2 S(1) emission-weighted mean temperature (T) as a function of density (n) for our simple one-dimensional PDR models of the warm H2 in Leo P (see Methods for details). These calculations assume a slab symmetry for the emitting gas, with a thickness L = 1 pc and a uniform density as indicated in the figure. The slab is illuminated by the radiation field produced by the O star in Leo P, which has a strength of χ = 200 in Habing units50. Results are shown for three different values for the cosmic ray (CR) ionization rate: ζH = 10−19 s−1 (black line), ζH = 10−18 s−1 (blue line) and ζH = 10−17 s−1 (red line).
Supplementary information
Supplementary Information
This file contains further descriptions of the JWST MIRI-MRS observation design; the impacts of our assumptions on the warm H2 temperature and mass limits; an alternative measurement of the upper limit on LCO; and implications for Leo P’s total H2 mass and CO-to-H2 conversion factor.
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Telford, O.G., Sandstrom, K.M., McQuinn, K.B.W. et al. Molecular hydrogen in the extremely metal- and dust-poor galaxy Leo P. Nature 642, 900–904 (2025). https://doi.org/10.1038/s41586-025-09115-7
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DOI: https://doi.org/10.1038/s41586-025-09115-7