Extended Data Fig. 7: Quaternary interactions in ROOLFirm and inter-tetramer interactions in ROOLFirm and ROOLEfa.

a, Front view of the ROOLFirm dimer stabilized by four key interactions, the close-up views of which are shown in panels c–f with map rendered as transparent surface (σ = 4.16). b, Side view of the inter-tetramer interface of ROOLFirm, the close-up views of which are shown in panels g and h with map rendered as transparent surface (σ = 4.16). i, Side view of the inter-tetramer interface of ROOLEfa (viewed similarly to ROOLFirm in b), the close-up views of which are shown in panels j and k with map rendered as transparent surface (σ = 2.88).