Extended Data Fig. 9: Connectivity of neurons of interest in the VNC and the brain.
From: Selective presynaptic inhibition of leg proprioception in behaving Drosophila
a, Hook axons, chief 9A neurons presynaptic to hook axons, and the top two descending neurons presynaptic to the chief 9A neurons in the male VNC connectome (MANC). A, anterior; L, left. b, Top two descending neurons presynaptic to the chief 9A neuron in the female VNC connectome (FANC). c, Outputs of chief 9A neurons onto different neuron types (MANC connectome). Black bars, output onto hook axons; L, left side of VNC; R, right side of VNC; 1, front leg neuromere; 2, middle leg neuromere; 3, hind leg neuromere. d, Connectivity of descending neurons with GABAergic neurons presynaptic to claw and hook axons. Descending neurons known to drive walking and grooming are indicated. Neurotransmitter predictions are from matched descending neurons in MANC81. e, Connectivity between descending neurons and 9A neurons. Numbers indicate connection strength to 9A as percent input synapses (top two rows) or absolute synapses (bottom two rows). Synapses from all DNg12 were summed. For “Other 9A” neurons, percent input synapses were averaged and absolute synapses were summed. f, Outputs of DNg74 in the VNC (MANC connectome). g, Inputs of DNg74 in the brain (FlyWire connectome). GNG, gnathal ganglia; AVLP, anterior ventrolateral protocerebrum; SAD, saddle; ICL, inferior clamp.
