Extended Data Fig. 3: Mice vaccinated with toxins and NTAs by RI have less epithelial damage to colons and ceca.
From: Mucosal vaccination clears Clostridioides difficile colonization
a,b, Histopathology scores of colons (a) and caeca (b). c, Representative haematoxylin & eosin (H&E) images of colons and caeca from each group of vaccinated mice at 3 days post infection with C. difficile R20291. Scale bar, 40 μm at 10x magnification. [3a-b] shown as mean +/− SEM. n = 5 per group. Statistical significance was calculated by means of [(a-b)] one-way ANOVA with Tukey’s correction; *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, ****P ≤ 0.0001. n = 5 per group. Total histology score is the summation of oedema, inflammation, and epithelial injury scores.
