Extended Data Fig. 3: Histopathological evaluation of the nonhuman primate (NHP) liver at three months following a single IT dose of 60 mg C16-siRNA.
From: Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates
Representative H&E staining of NHP liver (H = hepatocyte; S = sinusoid; KC = Kupffer cell). There were no remarkable microscopic findings. Three animals were analyzed per group with similar results.
