Extended Data Fig. 3: Cross-talk between Ccl19-Cre+ cells and professional antigen presenting cells during the induction of LacZ-specific T cell responses. | Nature Immunology

Extended Data Fig. 3: Cross-talk between Ccl19-Cre+ cells and professional antigen presenting cells during the induction of LacZ-specific T cell responses.

From: Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8+ T cells

Extended Data Fig. 3

The indicated bone marrow chimeric mice were generated and vaccinated i.v. with Ad-LacZ/FlexON. (a and b) The frequency of bgal497 tetramer+ CD8+ T cells was monitored in blood. Values indicate mean±s.e.m. for each time point. Pooled data from 2 independent experiments with n = 10 (Ctrl to Ccl19-Cre) to 8 (H2-Kb−/− to Ccl19-Cre) mice [(a)] and n = 5 (Ctrl to Ccl19-Cre) and 5 (Batf3−/− to Ccl19-Cre) mice [(b)]. Statistical analysis was performed using two-way analysis of variance (ANOVA) with Bonferroni multiple comparison test [(a) and (b)] *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. Exact P values are provided in the Source Data.

Source data

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