Extended Data Fig. 7: The expression profile of Nrp1 in lung immune cells.
From: Neuropilin-1 mediates lung tissue-specific control of ILC2 function in type 2 immunity
a, c-e Wild-type mice were challenged with bleomycin (2 mg/kg body weight) intranasally to induce fibrosis, and subsequently were treated with EG00229 or DMSO control for three weeks. (a) H&E staining of the representative lung tissue. (b) Nrp1 expression in lung immune cells from WT mice was analyzed by flow cytometry. (c-e) Absolute numbers of lung macrophages (n = 14 for DMSO, n = 11 for EG00229 in c), DCs and Treg cells (n = 5 for DMSO, n = 4 for EG00229 in d-e) in each group of mice. Each symbol represents an individual mouse (c-e). Data are representative of at least 3 independent experiments and are presented as mean ± SEM.
