Extended Data Fig. 7: Cytokine secretion from LTBI and RSTR PBMC following ESAT6/CFP10 stimulation. | Nature Immunology

Extended Data Fig. 7: Cytokine secretion from LTBI and RSTR PBMC following ESAT6/CFP10 stimulation.

From: Specific CD4+ T cell phenotypes associate with bacterial control in people who ‘resist’ infection with Mycobacterium tuberculosis

Extended Data Fig. 7

(a) Heatmap showing paired t-statistic of cytokine expression levels between ESAT6/CFP10 and DMSO stimulations from supernatants among RSTR (n = 18) and LTBI (n = 20) donors at 6, 12, 24, and 48 hours after stimulation. (b) Box plots showing the median and interquartile range of cytokine mean fluorescence intensities at the timepoint that exhibited the highest signal identified as in a. Whiskers represent minima and maxima. Significance was calculated by two-sided student’s t-test. n.s. (not significant), p-value > 0.05; *, p-value < 0.05; **, p-value < 0.01; ***, p-value < 0.001.

Back to article page