Extended Data Fig. 9: Representative staining of CXCR3+CCR6+ TH1 cells and IFN-γ+ CD4+ T cell frequencies.

(a) Representative staining for CXCR3+CCR6+ TH1 cells in ESAT6/CFP10-specific CD4+ T cells from a participant in the validation household contact cohort. (b) Median and interquartile range of frequencies of CXCR3+CCR6+ TH1 and IFN-γ+ CD4+ T cells in ESAT6/CFP10-specific CD4+ T cells or Mtb lysate-specific CD4+ T cells among RSTR (n = 17) and LTBI (n = 20). Whiskers represent minima and maxima. Significance was determined by two-sided Wilcoxon rank-sum tests.