Extended Data Fig. 3

(A) Expression of selected genes by PD-1⁺CD8⁺ T cells similar to Fig. 2c are indicated on the UMAP (purple: high expression, gray: low expression). (B) Top 20 reactome pathway analysis of genes up-regulated in dual-ICB after cycle 1 (pseudobulk analysis). –log FDR of indicated gene-sets are indicated by the bar length.