Extended Data Fig. 4: Pathogen-induced TFH phenotypes correlate tailored B cell responses. | Nature Immunology

Extended Data Fig. 4: Pathogen-induced TFH phenotypes correlate tailored B cell responses.

From: Divergent cytokine and transcriptional signatures control functional T follicular helper cell heterogeneity

Extended Data Fig. 4

a, Gating strategy to identify GC and MBC populations. b, Analysis of B220+IgDloCD95+CD38− GC B cells from ZsGreen_T-bet reporter mice infected with indicated pathogens at early peak GC response. (b) Correlation of frequency of GC B to the ratio of TEFF/TFH cells and to ZsGreen_T-bet reporter expression gMFI across infections. Data show experiments of 6–10 mice per group. Statistical tests: Pearson correlation of two-tailed P value.

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