Extended Data Fig. 1: Context of the study cohort.
a, Epidemiology of SARS-CoV-2 infection in England prior to, and during the study period by region. Evelina London Children’s Hospital is in central London and provides tertiary immunology, infectious diseases, cardiology and intensive care to children in south-east England in collaboration with other tertiary centers (referred to ‘approximate catchment’). Data from the UK Government (https://coronavirus.data.gov.uk/) accessed on 22nd June 2020. ‘Index case’ denotes the first case of PIMS-TS identified at Evelina London Children’s Hospital. b, Flow chart of recruitment to the study cohort. c, Heat map of prevalence of clinical features in MIS-C (PIMS-TS in UK terminology, and Kawasaki-like disease in some continental European cohorts (Supplementary Table 4)) and two recent European Kawasaki disease (KD) cohorts. d, Clinical features of MIS-C / PIMS-TS in comparison with two recent European KD cohorts.
