Extended Data Fig. 3: Impact on hyperkalaemia of salt substitute versus usual salt in participant subgroups by selected baseline characteristics.

The error bar is the risk ratio(RR) and its 95% confidence interval of hyperkalemia for salt substitute versus usual salt in each subgroup, obtained by generalized linear mixed models with adjustment for clustering. The p value was two-sided and was not adjusted for multiple comparison. Health conditions included any of the following: hypertension, diabetes mellitus, coronary heart disease, stroke, chronic kidney disease, cancer, chronic obstructive pulmonary disease or being bedridden. Risk of hyperkalemia was defined high if the participant met any of the following at baseline: serum potassium > 5.5 mmol/l, using any medication that may elevate potassium (ACEI/ARBs, potassium-sparing diuretics, beta-blockers), with history of renal disease and eGFR < 60 ml/min*1.73 m3.