Extended Data Fig. 3: eGFR in subset of participants.

Change in eGFR in 47 participants with iohexol measured GFR. The effect of semaglutide compared to placebo on estimated GFR was calculated using a MMRM model with two-sided P-values and with fixed effects for treatment, visit, baseline log-transformed UACR, the interaction between treatment and visit, and the interaction between baseline and estimated GFR. Numbers in the lower panel represent the numbers contributing to the mean.