Extended Data Fig. 4: Diastolic blood pressure over time.

Change from baseline in diastolic blood pressure. The effect of semaglutide compared to placebo on estimated diastolic blood pressure was calculated using a MMRM model with two-sided P-values and with fixed effects for treatment, visit, baseline log-transformed UACR, the interaction between treatment and visit, and the interaction between baseline and diastolic blood pressure. Numbers in the lower panel represent the numbers contributing to the mean.