Extended Data Fig. 6: Associations of Endogenous Taxa at Species, Genus, Family, Order and Class Level with CDI Recurrence and VE303 Abundance.
Effect-size bar plots for all organisms associated with CDI recurrence or non-recurrence (linear mixed effects [LME] model, Results are shown for taxa with un-adjusted p-value < 0.05 computed using the t-statistic.) at the level of A, species, B, genus, C, family, D, order, and E, class. Taxa in the right half of each plot are associated with non-recurrence; those in the left half are associated with recurrence. Bars depict the model effect size estimates for taxa-outcome correlations. Vertical annotations on the right indicate whether taxa were correlated with total VE303 abundance up to Day 14 (LME model); boxes indicate the model estimates for positive or negative correlation with VE303; stars show the level of significance level of correlation with p-values computed using the t-statistic and adjusted for multiple hypotheses by the Benjamini-Hochberg procedure.
