Extended Data Fig. 1: Estimated changes in time (min/day) in MVPA, LPA, SB, and sleep, as measured by accelerometry among the usual care (A), early TRE (B), late TRE (C), and self–selected TRE (D) groups after the 12–week intervention.

Two-sided P value from multivariate analysis of variance with Lawley-Hotelling trace test. Changes were estimated from the isometric log-ratio coordinates between the group compositional means at the 12-week measurement relative the overall compositional mean at baseline. MVPA, moderate-to-vigorous physical activity; LPA, light physical activity; SB, sedentary behavior; TRE, time-restricted eating.