Extended Data Fig. 4: Glucose levels during a 24–hour period as measured by continuous glucose monitoring over 14 days in both the baseline and the last 2 weeks of the 12–week intervention for men and women in the usual care (A and E), early TRE (B and F), late TRE (C and G), and self-selected TRE (D and H) groups.

The solid lines represent mean glucose levels, and the shaded area shows the 95% confidence interval. The color intensity of the eating window for time-restricted eating (TRE) groups corresponds to the number of participants having their meals at that specific time of day.