Table 1 Patient characteristics of the study cohorts at baseline

From: Implementation of a national AI technology program on cardiovascular outcomes and the health system

 

FFR-CT unavailable

FFR-CT available

P value

 

n (%)

n (%)

 
 

35,688 (39.4)

54,865 (60.6)

 

Demographics

 Age at index CT scan (years)

58 (49, 67)

59 (50, 68)

<0.0001

 Female

17,141 (48.0)a

26,393 (48.2)a

0.59

 Type 1 diabetes mellitus

454 (1.3)

707 (1.3)

0.84

 Type 2 diabetes mellitus

4,869 (13.6)

7,516 (13.7)

0.82

 Hyperlipidemia

8,397 (23.5)

12,724 (23.2)

0.24

 Hypertension

14,788 (41.4)

21,905 (39.9)

<0.0001

 Angina

6,457 (18.1)

9,843 (17.9)

0.57

 Myocardial Iifarction

1,597 (4.5)

2,355 (4.3)

0.19

 Valve disorder

3,667 (10.3)

4,890 (7.9)

0.03

 Heart failure

4,014 (11.2)

5,362 (9.8)

<0.0001

 TIA

341 (1.0)

454 (0.8)

0.048

 Cerebral infarction

681 (1.9)

952 (1.7)

0.06

 Atherosclerosis

520 (1.5)

788 (1.4)

0.79

 Aortic aneurysm

1,015 (2.8)

1,475 (2.7)

0.16

 COPD

3,597 (10.1)

4,401 (9.3)

0.0038

 Kidney disease

2,556 (7.2)

3,496 (6.4)

<0.001

Medicationsb

n = 34,554

n = 51,602

 

 ACE inhibitors

7,635 (22.1)

11,502 (22.3)

0.50

 Antiplatelets

10,282 (29.8)

15,592 (30.2)

0.15

 Beta blockers

10,313 (29.9)

16,066 (31.1)

<0.0001

 Calcium channel blockers

6,239 (18.1)

9,887 (19.2)

<0.0001

 Statins

16,960 (49.1)

26,434 (51.2)

<0.0001

 Vitamin K antagonist

1,096 (3.2)

1,167 (2.3)

<0.0001

 Factor Xa

2,794 (8.1)

4,723 (9.2)

<0.0001

 Lipid-lowering medications

699 (2.0)

1,266 (2.5)

<0.0001

  1. Data are presented as number and percentage or number and 95% CI or IQR.
  2. Wilcoxon–Mann–Whitney rank-sum and chi-square tests were used with a two-sided P value <0.05 considered significant.
  3. aAmong these patients, 0.14% not specified as female or male.
  4. bPrescribed medications per patient over 2 years.
  5. TIA, transient ischemic attack; ACE, angiotensin-converting enzyme.
  6. Diagnostic codes (ICD) from the HES were used to determine patient comorbidities.